Sepsis remains one of the leading causes of death in intensive care units worldwide. Despite significant progress in early detection and management, antibiotic dosing protocols often f
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The European Society of Intensive Care Medicine (ESICM) convened an international panel of experts to develop evidence-based guidelines on fluid resuscitation volumes for adult critically ill patient
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Sepsis remains the leading cause of death in burn care, yet early recognition is complicated by persistent hyperinflammatory responses and altered baseline physiology following ma
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For decades, progress in developing new treatments for critical illnesses such as sepsis, acute respiratory distress syndrome (ARDS), and trauma has been stalled by one fundamental challenge: althoug
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When a critically ill patient arrives in the emergency department, physicians must make rapid, high-stakes decisions related to infection and whether that infection is bacterial or viral. There are...
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Sepsis frequently results in acute kidney injury, prolonging hospital stay and increasing mortality risk. Incidence estimates range from 35–50% in sepsis and rise to 50–70% in intensive car
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Healthcare systems spend heavily on chronic disease once symptoms emerge, yet many conditions are preventable or better managed with earlier intervention. Artificial intelligence is shiftin
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13 September is World Sepsis Day (WSD), a global movement uniting individuals, healthcare professionals, and organisations to confront one of the world’s deadliest yet most preventable cond
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Vasopressors are standard therapy for sepsis-induced hypotension and shock, traditionally given via central venous catheters (CVCs) due to concerns about tissue injury from peripheral intravenous...
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Sepsis is a life-threatening, dysregulated immune response often leading to hypotension and multisystem organ dysfunction, with acute kidney injury (AKI) being the most common organ failure in critic
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